The Brew of Infection is a throwable potion that has different infection effects depending on what it hits. If a stone block, cobblestone block or stone brick block is hit, the block will be infected with a silverfish, which will emerge when the block is broken. If the potion hits a villager it will be infected and turn into a zombie villager. If the potion hits any other player or creature, they will be momentarily frozen as they clear the worms off themselves.

The Brew of Infection is created in a kettle using the recipe found in the book Witchcraft: Brews & Infusions. Into the pot, throw Toe of Frog, Creeper Heart, a Wormy Apple, Belladonna Flower, Rotten Flesh and Mutandis.

This brew has no chance to get a bonus brew.